LA @ SF prediction: AI-powered NFL analysis
NFL · Week 10 · Levi's Stadium
VS
09/11/2025
Kickoff 22:25 (Paris time)
Kickoff 22:25 (Paris time)
Analysis published before kickoff
Best odds across books (CLV)
Transparent method
Spread
LA
-5.5
LA
Spread
SF
+5.5
SF
Total (O/U)
49.5
points
nflverse reference lines
Our picks for this match
Official
SF +5.5
Edge vs market
—
Odds
1.91
Market
Spread
Pick taken on 08/11 à 01:00 — odds at the time: 1.91 (CLV tracking)
INJURIES & ABSENCES
Los Angeles RamsMyles Garrett
Jordan Whittington
Kam Curl
Kamren Kinchens
Nate Landman
Omar Speights
San Francisco 49ersDe'Zhaun Stribling
Jake Tonges
Eddy Pineiro
Kaelon Black
Brayden Willis
Deebo Samuel Sr.
Official injury report — ESPN feed, updated daily.
Key Factors
Points scored/g
33.8vs30.0
Points allowed/g
21.6vs21.0
Pass EPA
3.78vs7.56
Turnover diff.
0.4vs-0.2
Record
14-6vs12-5
Roof: outdoors
Surface: grass
Levi's Stadium — Santa Clara, CA
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Head-to-head
3LA
SF2
02/10/25SF — LA26 – 23
12/12/24LA — SF12 – 6
22/09/24SF — LA24 – 27
07/01/24LA — SF21 – 20
17/09/23SF — LA30 – 23
Form & statistics
Team Comparison
8 of 65 model features (last 5-10 games)
LA
STAT
SF
27.2
22.8
13.2
22.6
387
359
282
254
105
105
+0.8
-0.2
+6.6
+9.8
38.2%
47.1%
Frequently asked questions
When was LA @ SF played?
This NFL game was played on 2025-11-09.
Where can I find the prediction for LA @ SF?
This ProbWin page shows the predictions our model published before the game (spreads and totals), the key stats for both sides, and the settled result — every prediction is kept, win or lose, in our public track record.
How are these predictions calculated?
Our NFL statistical models are trained on league history and recomputed daily from team and player stats plus market odds. Every prediction is published before the game and its result is settled publicly.
