NO @ BUF prediction: AI-powered NFL analysis
NFL · Week 4 · New Era Field
VS
28/09/2025
Kickoff 19:00 (Paris time)
Kickoff 19:00 (Paris time)
Analysis published before kickoff
Best odds across books (CLV)
Transparent method
Spread
NO
+15.5
NO
Spread
BUF
-15.5
BUF
Total (O/U)
48.5
points
nflverse reference lines
Our picks for this match
Official
NO +15.5
Edge vs market
—
Odds
1.91
Market
Spread
Pick taken on 27/09 à 02:00 — odds at the time: 1.91 (CLV tracking)
AI Trend
OVER 48.5
Edge vs market
—
Odds
1.91
Market
Totals (points)
Pick taken on 27/09 à 02:00 — odds at the time: 1.91 (CLV tracking)
INJURIES & ABSENCES
New Orleans SaintsAudric Estime
Zach Wood
Isaiah Stalbird
Chase Young
Chris Olave
Christen Miller
Buffalo BillsAr'maj Reed-Adams
Ed Oliver
Jalon Kilgore
Jude Bowry
Skyler Bell
T.J. Sanders
Official injury report — ESPN feed, updated daily.
Key Factors
Points scored/g
17.6vs32.6
Points allowed/g
17.8vs25.4
Pass EPA
-1.45vs6.14
Turnover diff.
0.4vs0.0
Record
6-11vs12-5
Roof: outdoors
Surface: a_turf
New Era Field — Orchard Park, NY
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Head-to-head
1NO
BUF1
25/11/21BUF — NO31 – 6
12/11/17NO — BUF47 – 10
Form & statistics
Team Comparison
8 of 65 model features (last 5-10 games)
NO
STAT
BUF
15.2
31.6
28.4
25.6
310
389
219
230
90
159
-0.2
+1.4
-9.0
+14.3
28.1%
44.4%
Frequently asked questions
When was NO @ BUF played?
This NFL game was played on 2025-09-28.
Where can I find the prediction for NO @ BUF?
This ProbWin page shows the predictions our model published before the game (spreads and totals), the key stats for both sides, and the settled result — every prediction is kept, win or lose, in our public track record.
How are these predictions calculated?
Our NFL statistical models are trained on league history and recomputed daily from team and player stats plus market odds. Every prediction is published before the game and its result is settled publicly.
